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BioMed Research International
Volume 2015, Article ID 504187, 16 pages
Research Article

Sialic Acid Expression in the Mosquito Aedes aegypti and Its Possible Role in Dengue Virus-Vector Interactions

1Molecular Biology and Biotechnology Department, Biomedical Research Institute, National University of México (UNAM), 04510 México City, Mexico
2Structural and Functional Glycobiology Unit, UMR 8576 CNRS, University of Sciences and Technologies of Lille, 59655 Villeneuve d’Ascq, France
3Biochemistry Department, Faculty of Medicine, UNAM, 04510 México City, Mexico
4CISEI, National Institute of Public Health, 62100 Cuernavaca, MOR, Mexico
5Infectomics and Molecular Pathogenesis Department, CINVESTAV-IPN, 07360 México City, Mexico
6Virology Department, National Respiratory Institute (INER), 14050 México City, Mexico

Received 25 July 2014; Accepted 24 September 2014

Academic Editor: Michael J. Conway

Copyright © 2015 Jorge Cime-Castillo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplementary Figure 1: CLUSTALW analysis of Aedes aegypti CSAS.

Supplementary Figure 2: MAA Lectin in the midguts of Aedes aegypti and the SGs of Aedes aegypti and Drosophila melanogaster.

Supplementary Figure 3: DENV interaction with Aedes aegypti midgut.

Supplementary Figure 4: Mass analysis of ions obtained with MALDI–ToF and the equivalent peptide sequences.

Supplementary Figure 5: SNA staining in Aedes aegypti mosquito and Drosophila melanogaster tissues in the presence or absence of C. perfringens sialidase.

Supplementary Table 1. Hemagglutinating activity of DENV.

  1. Supplementary Materials