BioMed Research International / 2015 / Article / Tab 3

Clinical Study

Disorders of MicroRNAs in Peripheral Blood Mononuclear Cells: As Novel Biomarkers of Ankylosing Spondylitis and Provocative Therapeutic Targets

Table 3

Expression of two microRNAs by real-time PCR validated.

Control group/AS group (fold) valueAS group before/after therapy (fold) value

hsa-miR-29a 16.22 (16.22)0.0020.31 (3.18)0.049
hsa-miR-126-3p3.76 (3.76)0.0460.45 (2.20)0.035

The expression levels of these 2 microRNAs were significantly lower in AS group than in control group. And expressions of them were dramatically upregulated after 12-week etanercept treatment (fold changes >2, < 0.05).

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