Review Article

Current and Emerging Cell Culture Manufacturing Technologies for Influenza Vaccines

Table 3

List of influenza vaccines in clinical studies (http://www.clinicaltrials.gov/).

TechnologyCompanyPhase of development

Recombinant (VLP)
VLP (HA, NA, and M) insect cellNovavaxClinical trial phase 2

Vectors
AdenovirusPaxvaxClinical trial phase 2
AdenovirusVaxartClinical trial phase 1

Cell-based LAIV
MDCK H5N1MedImmunePreclinical
dNS1-VeroVivaldi BiosciencesPhase 1
dNS1-VeroAVIR Green Hills BiotechPhase 2