Proteomic Changes of Tissue-Tolerable Plasma Treated Airway Epithelial Cells and Their Relation to Wound Healing

Figure 2

Time course of wound healing processes of S9 epithelial cells. (a) The regenerated wound area was calculated by taking the average of six representative wounds per culture plate/dose and time point. Significant differences (see ) were observed after 96 h and 120 h between 120 s plasma treated and untreated control samples. Plasma application for 30 s and 60 s provided no significant effect on wound healing, < 0.05 (Student’s -test, ). (b) Cell cultures of plasma treated and untreated samples were cut in order to create circular artificial wounds. The outer blue line represents the primary wound border. The red line represents the current healing border after 24 h, 48 h, 72 h, 96 h, and 120 h. For every time point, the effect of 120 s TTP treatment on wound healing is shown in comparison to untreated samples “control.”

(a)

(b)