Swimming Activity Prevents the Unloading Induced Loss of Bone Mass, Architecture, and Strength in Rats

Figure 5

Unloading caused a significant decrease in the cortical volume (CtV) and cortical thickness (CtTh), at the diaphysis of tibias of hindlimb-suspended rats when compared to the controls (HS versus Control; ). CtV was partially preserved by swimming exercises (HS + Swim versus HS, ; HS + Swim versus HS + WB, ) but not by regular weight bearing (HS versus HS + WB, ). Different signs indicate significant difference ().