S100B Inhibitor Pentamidine Attenuates Reactive Gliosis and Reduces Neuronal Loss in a Mouse Model of Alzheimer’s Disease

Figure 2

(a) Electrophoretic mobility shift assay (EMSA) and the relative (b) densitometric analysis showing the effect following 7 days of intrahippocampal injection of pentamidine (0.05–5 g/mL/day) on the expression of NF-B in A-injected mice. Results are expressed as mean ± SEM of experiments performed in triplicate. versus vehicle-treated mice; and versus A-treated mice.

(a)

(b)