Osteopontin Involves Cisplatin Resistance and Poor Prognosis in Oral Squamous Cell Carcinoma

Table 3

Correlation between the clinicopathological features and 5-year progression-free survival in oral squamous cell carcinoma.

Variables	Number of patients	Cumulative 5-year PFS rate		5-year PFS
				HR (95% CI)
Age
60	102	23.2%	0.992
60	19	26.3%
Gender
Male	117	23.2%	0.372
Female	4	50.0%
Stage
IVa	35	38.7%		1
IVb	86	20.0%		2.097 (1.255–3.505)	0.005
T stage
1-2	28	26.2%	0.735
3-4	93	23.4%
N stage
Negative	40	47.3%		1
Positive	81	12.0%		1.940 (1.148–3.279)	0.013
Chemotherapy
PF	83	23.0%	0.465
TPF	38	26.4%
Alcohol
Never	30	33.1%	0.206
Yes	91	20.8%
Smoking
Never	29	39.8%	0.009
Yes	92	19.0%
Betel nuts
Never	31	22.7%	0.337
Yes	90	23.5%
OPN
Negative	27	61.8%	<0.001	1
Positive	94	13.2%		2.509 (1.256–5.009)	0.009

CI, confidence interval; HR, hazard ratio.
Indicates significantly difference ().