Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2015, Article ID 510514, 7 pages
http://dx.doi.org/10.1155/2015/510514
Research Article

Prevalence and Possible Risk Factors of Low Bone Mineral Density in Untreated Female Patients with Systemic Lupus Erythematosus

1Department of Rheumatology, First Affiliated Hospital of the Medical School, Xi’an Jiaotong University, Xi’an, Shaanxi 710061, China
2Department of Epidemiology and Biostatistics, School of Public Health, Xi’an Jiaotong University, Xi’an, Shaanxi 710061, China

Received 8 October 2014; Accepted 19 January 2015

Academic Editor: Hiroshi Tanaka

Copyright © 2015 Yi-Ning Sun et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. M. Furukawa, C. Kiyohara, H. Tsukamoto et al., “Prevalence of and risk factors for low bone mineral density in Japanese female patients with systemic lupus erythematosus,” Rheumatology International, vol. 31, no. 3, pp. 365–376, 2011. View at Publisher · View at Google Scholar · View at Scopus
  2. C. Mendoza-Pinto, M. García-Carrasco, H. Sandoval-Cruz et al., “Risks factors for low bone mineral density in pre-menopausal Mexican women with systemic lupus erythematosus,” Clinical Rheumatology, vol. 28, no. 1, pp. 65–70, 2009. View at Publisher · View at Google Scholar · View at Scopus
  3. K. Almehed, E. H. Forsblad d', G. Kvist, C. Ohlsson, and H. Carlsten, “Prevalence and risk factors of osteoporosis in female SLE patients—extended report,” Rheumatology, vol. 46, no. 7, pp. 1185–1190, 2007. View at Publisher · View at Google Scholar · View at Scopus
  4. M. García-Carrasco, C. Mendoza-Pinto, R. O. Escárcega et al., “Osteoporosis in patients with systemic lupus erythematosus,” Israel Medical Association Journal, vol. 11, no. 8, pp. 486–491, 2009. View at Google Scholar · View at Scopus
  5. T. Y. Zhu, J. F. Griffith, S.-K. Au et al., “Incidence of and risk factors for non-vertebral and vertebral fracture in female Chinese patients with systemic lupus erythematosus: a five-year cohort study,” Lupus, vol. 23, no. 9, pp. 854–861, 2014. View at Publisher · View at Google Scholar
  6. K. Almehed, S. Hetényi, C. Ohlsson et al., “Prevalence and risk factors of vertebral compression fractures in female SLE patients,” Arthritis Research and Therapy, vol. 12, no. 4, pp. R153–R159, 2010. View at Google Scholar
  7. M. García-Carrasco, C. Mendoza-Pint, C. Riebeling et al., “Influence of prevalent vertebral fractures on the quality of life of patients with systemic lupus erythematosus,” Israel Medical Association Journal, vol. 13, no. 6, pp. 333–337, 2011. View at Google Scholar · View at Scopus
  8. I. E. M. Bultink, M. Vis, I. E. van der Horst-Bruinsma, and W. F. Lems, “Inflammatory rheumatic disorders and bone,” Current Rheumatology Reports, vol. 14, no. 3, pp. 224–230, 2012. View at Publisher · View at Google Scholar · View at Scopus
  9. M. C. Hochberg, “Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus,” Arthritis and rheumatism, vol. 40, no. 9, article 1725, 1997. View at Google Scholar · View at Scopus
  10. C. Bombardier, D. D. Gladman, M. B. Urowitz et al., “Derivation of the SLEDAI: a disease activity index for lupus patients,” Arthritis and Rheumatism, vol. 35, no. 6, pp. 630–640, 1992. View at Publisher · View at Google Scholar · View at Scopus
  11. C.-S. Yee, N. Crabtree, J. Skan et al., “Prevalence and predictors of fragility fractures in systemic lupus erythematosus,” Annals of the Rheumatic Diseases, vol. 64, no. 1, pp. 111–113, 2005. View at Publisher · View at Google Scholar · View at Scopus
  12. T. C. Salman-Monte, V. Torrente-Segarra, J. Muñoz-Ortego, S. Mojal, and J. Carbonell-Abelló, “Prevalence and predictors of low bone density and fragility fractures in women with systemic lupus erythematosus in a Mediterranean region,” Rheumatology International, 2014. View at Publisher · View at Google Scholar
  13. J. Jacobs, L.-A. Korswagen, A. M. Schilder et al., “Six-year follow-up study of bone mineral density in patients with systemic lupus erythematosus,” Osteoporosis International, vol. 24, no. 6, pp. 1827–1833, 2013. View at Publisher · View at Google Scholar · View at Scopus
  14. C. C. Mok, A. Mak, and K. M. Ma, “Bone mineral density in postmenopausal Chinese patients with systemic lupus erythematosus,” Lupus, vol. 14, no. 2, pp. 106–112, 2005. View at Publisher · View at Google Scholar · View at Scopus
  15. C. Lee, O. Almagor, D. D. Dunlop et al., “Association between African American race/ethnicity and low bone mineral density in women with systemic lupus erythematosus,” Arthritis Care and Research, vol. 57, no. 4, pp. 585–592, 2007. View at Publisher · View at Google Scholar · View at Scopus
  16. S. Banno, Y. Matsumoto, T. Naniwa et al., “Reduced bone mineral density in Japanese premenopausal women with systemic lupus erythematosus treated with glucocorticoids,” Modern Rheumatology, vol. 12, no. 4, pp. 323–328, 2002. View at Publisher · View at Google Scholar · View at Scopus
  17. H. Chen and K. Y. Kubo, “Bone three-dimensional microstructural features of the common osteoporotic fracture sites,” World Journal of Orthopedics, vol. 5, no. 4, pp. 486–495, 2014. View at Publisher · View at Google Scholar
  18. R. M. R. Pereira, J. F. de Carvalho, and E. Canalis, “Glucocorticoid-induced osteoporosis in rheumatic diseases,” Clinics, vol. 65, no. 11, pp. 1197–1205, 2010. View at Publisher · View at Google Scholar · View at Scopus
  19. C. A. Pineau, M. B. Urowitz, P. J. Fortin, D. Ibanez, and D. D. Gladman, “Osteoporosis in systemic lupus erythematosus: factors associated with referral for bone mineral density studies, prevalence of osteoporosis and factors associated with reduced bone density,” Lupus, vol. 13, no. 6, pp. 436–441, 2004. View at Publisher · View at Google Scholar · View at Scopus
  20. Y. Tang, H. Xie, J. Chen et al., “Activated NF-κB in bone marrow mesenchymal stem cells from systemic lupus erythematosus patients inhibits osteogenic differentiation through downregulating smad signaling,” Stem Cells and Development, vol. 22, no. 4, pp. 668–678, 2013. View at Publisher · View at Google Scholar · View at Scopus
  21. I. E. M. Bultink, W. F. Lems, P. J. Kostense, B. A. C. Dijkmans, and A. E. Voskuyl, “Prevalence of and risk factors for low bone mineral density and vertebral fractures in patients with systemic lupus erythematosus,” Arthritis & Rheumatism, vol. 52, no. 7, pp. 2044–2050, 2005. View at Publisher · View at Google Scholar · View at Scopus
  22. C. Mendoza-Pinto, M. García-Carrasco, H. Sandoval-Cruz et al., “Risk factors of vertebral fractures in women with systemic lupus erythematosus,” Clinical Rheumatology, vol. 28, no. 5, pp. 579–585, 2009. View at Publisher · View at Google Scholar · View at Scopus
  23. M. K. Garg, R. K. Marwaha, N. Tandon, K. Bhadra, and N. Mahalle, “Relationship of lipid parameters with bone mineral density in Indian population,” Indian Journal of Endocrinology and Metabolism, vol. 18, no. 3, pp. 325–332, 2014. View at Publisher · View at Google Scholar
  24. I.-K. Jeong, S. W. Cho, S. W. Kim et al., “Lipid profiles and bone mineral density in pre- and postmenopausal women in korea,” Calcified Tissue International, vol. 87, no. 6, pp. 507–512, 2010. View at Publisher · View at Google Scholar · View at Scopus
  25. K. S. Sarkis, L. A. Martini, V. L. Szejnfeld, and M. M. Pinheiro, “Low fatness, reduced fat intake and adequate plasmatic concentrations of LDL-cholesterol are associated with high bone mineral density in women: a cross-sectional study with control group,” Lipids in health and disease, vol. 11, pp. 37–44, 2012. View at Publisher · View at Google Scholar · View at Scopus
  26. A. Fisher, W. Srikusalanukul, M. Davis, and P. Smith, “Cardiovascular diseases in older patients with osteoporotic hip fracture: prevalence, disturbances in mineral and bone metabolism, and bidirectional links,” Clinical Interventions in Aging, vol. 8, pp. 239–256, 2013. View at Publisher · View at Google Scholar · View at Scopus
  27. G. N. Farhat, A. B. Newman, K. Sutton-Tyrrell et al., “The association of bone mineral density measures with incident cardiovascular disease in older adults,” Osteoporosis International, vol. 18, no. 7, pp. 999–1008, 2007. View at Publisher · View at Google Scholar · View at Scopus
  28. J. S. Chen, C. Hogan, G. Lyubomirsky, and P. N. Sambrook, “Women with cardiovascular disease have increased risk of osteoporotic fracture,” Calcified Tissue International, vol. 88, no. 1, pp. 9–15, 2011. View at Publisher · View at Google Scholar · View at Scopus
  29. G. G. Ribeiro, E. Bonfá, R. S. Neto et al., “Premature coronary artery calcification is associated with disease duration and bone mineral density in young female systemic lupus erythematosus patients,” Lupus, vol. 19, no. 1, pp. 27–33, 2010. View at Publisher · View at Google Scholar · View at Scopus
  30. M. Yamauchi, T. Yamaguchi, K. Nawata, K.-I. Tanaka, S. Takaoka, and T. Sugimoto, “Increased low-density lipoprotein cholesterol level is associated with non-vertebral fractures in postmenopausal women,” Endocrine, 2014. View at Publisher · View at Google Scholar · View at Scopus
  31. J. Frostegård, E. Svenungsson, R. Wu et al., “Lipid peroxidation is enhanced in patients with systemic lupus erythematosus and is associated with arterial and renal disease manifestations,” Arthritis and Rheumatism, vol. 52, no. 1, pp. 192–200, 2005. View at Publisher · View at Google Scholar · View at Scopus
  32. A. P. Sage, J. Lu, E. Atti et al., “Hyperlipidemia induces resistance to PTH bone anabolism in mice via oxidized lipids,” Journal of Bone and Mineral Research, vol. 26, no. 6, pp. 1197–1206, 2011. View at Publisher · View at Google Scholar · View at Scopus
  33. C. Mazière, V. Savitsky, A. Galmiche, C. Gomila, Z. Massy, and J.-C. Mazière, “Oxidized low density lipoprotein inhibits phosphate signaling and phosphate-induced mineralization in osteoblasts. Involvement of oxidative stress,” Biochimica et Biophysica Acta, vol. 1802, no. 11, pp. 1013–1019, 2010. View at Publisher · View at Google Scholar · View at Scopus
  34. C. Mazière, V. Salle, C. Gomila, and J.-C. Mazière, “Oxidized low density lipoprotein enhanced RANKL expression in human osteoblast-like cells. Involvement of ERK, NFkappaB and NFAT,” Biochimica et Biophysica Acta, vol. 1832, no. 10, pp. 1756–1764, 2013. View at Publisher · View at Google Scholar · View at Scopus
  35. C. Mazière, V. Salle, C. Gomila, and J.-C. Mazière, “Oxidized low density lipoprotein increases RANKL level in human vascular cells. Involvement of oxidative stress,” Biochemical and Biophysical Research Communications, vol. 440, no. 2, pp. 295–299, 2013. View at Publisher · View at Google Scholar · View at Scopus