Variations in Antioxidant Genes and Male Infertility

Table 1

Major antioxidant enzymes in spermatogenesis.

Enzyme	Name	Isoforms in human	Reference
NRF2	Nuclear factor erythroid 2-related factor 2	NRF2	[12]
SOD	Superoxide dismutase	SOD1, SOD2, SOD3	[13]
CAT	Catalase	CAT	[9]
NOS	Nitric oxide (NO) synthase	NOS-1, NOS-2, NOS-3	[14]
GST	Glutathione S-transferase	GSTA1–GSTA5, GSTZ1, GSTM1–GSTM5, GSTO1-GSTO2, GSTP1, GSTT1–GSTT4	[15]
PRX	Peroxiredoxin	PRX1–PRX6	[16, 17]
GPX	Glutathione peroxidase	GPX1–GPX8	[18]
TRX	Thioredoxin	TRX1, TXR2	[19]