(a)
(b)
Figure 2: The Cox’s regression model. Observed (denoted by square, diamonds and triangles points) and predicted (denoted by solid line) prognosis curves for the PDAC patients according to (a) univariate o and (b) multivariate Cox’s proportional hazard model analysis. As explained in the text, the stepwise procedure based on the likelihood ratio was used to select a model containing a statistically significant subset of prognosis factors. The three predicted prognosis curves in (b) are derived from step 3 (where three cytokines are included), step 4 (four cytokines included), and step 5 (five cytokines included) of this stepwise procedure. The predicted survival curves are adjusted to a logarithmic distribution function, as expected. The coefficient of determination R2 is illustrative of the model goodness of fit. As coefficient attested, these models would yield useful predictions, being the five cytokines multivariate model the most accurate, reaching a 92.6%. This means that our PI properly models approximately 93% of the survival variation.