Prognosis Relevance of Serum Cytokines in Pancreatic Cancer
Table 2
Prognosis factors in univariate analysis.
Variable
Overall survival
β
HR
95% CI
value
BDNF
0.005
1.005
1.000
1.009
0.034
HVEM/TNFRSF14
−0.079
0.924
0.858
0.996
0.038
IL-24
0.040
1.041
1.006
1.078
0.023
IL-29
0.012
1.012
1.002
1.023
0.021
Leptin R
0.008
1.008
1.001
1.015
0.018
LRP-6
0.027
1.027
1.004
1.051
0.022
ROBO4
0.002
1.002
1.000
1.004
0.045
Age
0.086
1.089
1.008
1.177
0.030
Clinical response
2.064
8.706
1.057
71.692
0.013
Cytokines
Overall model fit ()
β
HR
95% CI
value
IL-24 (1)
0.042
1.042
1.003
1.023
0.026
IL-29 (2)
0.014
1.014
1.005
1.081
0.017
β: coefficient provided by the Cox's regression model for a particular patient and cytokine; HR: hazard ratio (represents the factor by which the hazard changes for each one-unit increase of the cytokine expression); 95% CI: upper and lower limits of the confidence interval with a significance level of 0.05.