Research Article

Prognosis Relevance of Serum Cytokines in Pancreatic Cancer

Table 2

Prognosis factors in univariate analysis.

Variable Overall survival
βHR 95% CI value

BDNF 0.005 1.0051.000 1.009 0.034
HVEM/TNFRSF14−0.079 0.9240.858 0.996 0.038
IL-240.040 1.0411.006 1.078 0.023
IL-290.012 1.0121.002 1.023 0.021
Leptin R0.008 1.0081.001 1.015 0.018
LRP-60.027 1.0271.004 1.051 0.022
ROBO40.002 1.0021.000 1.004 0.045
Age 0.086 1.089 1.008 1.177 0.030
Clinical response 2.0648.706 1.057 71.692 0.013

Cytokines Overall model fit ()
βHR95% CI value

IL-24 (1)0.0421.0421.0031.0230.026
IL-29 (2)0.0141.0141.0051.0810.017

β: coefficient provided by the Cox's regression model for a particular patient and cytokine; HR: hazard ratio (represents the factor by which the hazard changes for each one-unit increase of the cytokine expression); 95% CI: upper and lower limits of the confidence interval with a significance level of 0.05.