BioMed Research International / 2015 / Article / Tab 2

Research Article

Analysis of Single Nucleotide Polymorphisms within ADAM12 and Risk of Knee Osteoarthritis in a Chinese Han Population

Table 2

The comparison of the 4 SNPs between the cases and controls.

GroupGenotype (frequency) rs1278279
G (%)A (%)GGGA + AAGG + GAAAGGAA

Control76.523.5121791851512115
Case75.025.09272154109210
ORa/1.06/1.17/0.83/0.88
95% CIa0.87 to 1.34/0.79 to 1.81/0.35 to 1.84/0.36 to 2.03
/n.s/n.s/n.s/n.s

GroupGenotype (frequency) rs3740199
G (%)C (%)GGGC + CCGG + GCCCGGCC

Control51.049.051149153475147
Case52.447.644120128364436
ORa/0.93/0.92/0.90/0.87
95% CIa0.76 to 1.14/0.58 to 1.49/0.54 to 1.52/0.48 to 1.61
/n.s/n.s/n.s/n.s

GroupGenotype (frequency) rs1871054
T (%)C (%)TTTC + CCTT + TCCCTTCC

Control50.849.252148151495249
Case35.764.32913588762976
ORa/1.84/1.64/2.65/2.78
95% CIa/1.57 to 2.23/1.01 to 2.74/1.72 to 4.14/1.56 to 4.95
/<0.0001/0.0348/<0.0001/0.0012

GroupGenotype (frequency) rs1044122
T (%)C (%)TTTC + CCTT + TCCCTTCC

Control56.343.762138163376237
Case57.942.151113139255125
ORa/0.94/0.98/0.76/0.83
95% CIa0.73 to 1.12/0.64 to 1.57/0.44 to 1.39/0.44 to 1.53
/n.s/n.s/n.s/n.s

ORs and 95% CIs were estimated using logistic regression analyses and adjusted for age, gender, and BMI.