Interleukin-1 β Modulates Melatonin Secretion in Ovine Pineal Gland: Ex Vivo Study

Figure 1

The effects of norepinephrine (NE, 10 μM), interleukin- (IL-) 1β (75 pg/mL), and mixture of NE with IL-1β on melatonin concentration (pg/mg of tissue) in the medium of pineal gland explants collected from saline- and lipopolysaccharide- (LPS-) treated ewes. Different lowercase letters indicate significant () differences within the saline-treated group; different capital letters indicate differences within the LPS-treated group; control: no NE/IL-1β treatment.