BioMed Research International / 2015 / Article / Tab 2

Research Article

Ureteral Involvement and Diabetes Increase the Risk of Subsequent Bladder Recurrence after Nephroureterectomy for Upper Urinary Tract Urothelial Carcinoma

Table 2

Univariate and multivariate analyses for variables significantly associated with subsequent bladder recurrence after RNU in 532 patients with UUT-UC.

Variable Univariate Multivariate
HR (95% CI)HR (95% CI)

Age (years)
 <651
 ≥650.819 (0.594–1.128)0.222
Gender
 Female1
 Male1.210 (0.878–1.669)0.245
Smoking
 No1
 Yes1.221 (0.838–1.778)0.298
BMI0.967 (0.909–1.028)0.277
eGFR (mL/min)
 <601
 >601.347 (0.757–2.396)0.312
Hemodialysis
 No11
 Yes1.603 (0.990–2.595)0.0551.791 (0.988–3.244)0.055
Chinese herbal medicine use
 No11
 Yes1.851 (1.012–3.386)0.046*1.387 (0.731–2.632)0.316
Hypertension
 No1
 Yes1.292 (0.868–1.922)0.207
DM
 No11
 Yes1.953 (1.241–3.074)0.004*1.821 (1.152–2.878)0.010*
Residency
 Nonarsenic1
 Arsenic0.775 (0.247–2.434)0.662
OP method
 Transperitoneal1
 Retroperitoneal1.097 (0.674–1.786)0.708
OP method
 Open1
 Laparoscopy1.420 (0.868–2.323)0.162
Grade
 Low1
 High0.994 (0.705–1.402)0.974
Ureteral involvement
 No 11
 Yes1.639 (1.189–2.260)0.003*1.838 (1.233–2.741)0.003*
Multiplicity
 No1
 Yes1.499 (0.953–2.356)0.080
T stage
 Ta, 11
 T21.135 (0.727–1.771)0.578
 T3, 40.914 (0.610–1.368)0.661
 Tis2.110 (0.770–5.785)0.147
N stage
 N01
 N1, 2, 30.394 (0.125–1.239)0.111

BMI: body mass index, DM: diabetes mellitus, HR: Hazard ratio, and CI: confidence interval.
*Significant difference, .

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