Insufficient Discriminatory Power of Matrix-Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry Dendrograms to Determine the Clonality of Multi-Drug-Resistant Acinetobacter baumannii Isolates from an Intensive Care Unit

Table 1

Characteristics of the isolates tested and ICU patients.

Isolate; number	Type of specimen	Sputum; grade^*	Antibiotics (susceptibility/MIC in μg/mL)				Age	Sex	Major disease condition related to; respiratory infection	Underlying major diseases	Clinical; outcome
			COL	IMI	CFT	LFX
1	Sputum, endotracheal aspirate	6	S ≤ 0.5	R ≥ 16	R ≥ 64	R ≥ 8	66	F	Pneumonia	Chronic kidney disease, septic arthritis	Discharged
2	Sputum	6	S ≤ 0.5	R ≥ 16	R ≥ 64	R ≥ 8	62	F	None	End-stage renal disease	Discharged
3	Endotracheal aspirate	6	S ≤ 0.5	R ≥ 16	R ≥ 64	R ≥ 8	67	M	Pneumonia	Rectosigmoid junction cancer	Expired
4	Sputum	6	S ≤ 0.5	S ≤ 0.25	S 8	R ≥ 8	29	M	None	Anti-NMDA receptor encephalitis	Discharged
5	Endotracheal aspirate	6	S ≤ 0.5	R ≥ 16	R ≥ 64	R ≥ 8	67	M	Pneumonia	Lung cancer	Expired
6	Endotracheal aspirate	6	S ≤ 0.5	R ≥ 16	R ≥ 64	R ≥ 8	72	F	Pneumonia	Myasthenia gravis, pseudomembranous colitis	Discharged
7	Endotracheal aspirate	6	R 16	R ≥ 16	R ≥ 64	R ≥ 8	61	M	Pneumonia	Pancreatic cyst	Expired
8	Sputum	5	S ≤ 0.5	R ≥ 16	R ≥ 64	R ≥ 8	49	F	Pneumonia	Acute lymphoblastic leukemia	Expired
9	Sputum	6	S ≤ 0.5	R ≥ 16	R ≥ 64	R ≥ 8	2	F	Pneumonia	Hypoxic ischemic encephalopathy	Discharged
10	Endotracheal aspirate	6	S ≤ 0.5	R ≥ 16	R ≥ 64	R ≥ 8	79	F	Pleural effusion, tracheostomy	Aortic regurgitation, chronic renal failure	Discharged
11	Sputum	6	S ≤ 0.5	R ≥ 16	R ≥ 64	R ≥ 8	75	M	Interstitial lung disease	Cholangiocarcinoma, upper GI bleeding	Expired
12^*	Sputum	6	S ≤ 0.5	R ≥ 16	R ≥ 64	R ≥ 8	71	M	Pneumonia	Urinary tract infection, osteomyelitis, invasive aspergillosis	Discharged
13	Endotracheal aspirate	6	S ≤ 0.5	R ≥ 16	R ≥ 64	R ≥ 8	49	M	None	Diffuse large B-cell lymphoma, bacterial meningitis	Expired
14	Endotracheal aspirate	6	S ≤ 0.5	R ≥ 16	R ≥ 64	R ≥ 8	71	M	None	Alzheimer’s disease, pneumothorax	Discharged
15	Endotracheal aspirate	6	S ≤ 0.5	R ≥ 16	R ≥ 64	R ≥ 8	81	M	Pneumonia	Chronic renal failure	Expired
16	Sputum	6	S ≤ 0.5	R ≥ 16	R ≥ 64	R ≥ 8	74	M	Pneumonia	Pneumothorax, acute renal failure	Expired
17	Sputum	6	S ≤ 0.5	R ≥ 16	R ≥ 64	R ≥ 8	78	M	Pneumonia	Acute pulmonary edema	Expired
18	Sputum	6	S ≤ 0.5	R ≥ 16	R ≥ 64	R ≥ 8	31	M	Pneumonia	Aplastic anemia, intracranial hemorrhage	Expired
19	Endotracheal aspirate	6	S ≤ 0.5	R ≥ 16	I 16	I 4	75	F	Pneumonia, pleural effusion	Wegener’s granulomatosis	Expired
20	Sputum	6	S ≤ 0.5	R ≥ 16	I 16	I 4	21	M	Pneumonia	Cerebral palsy, Dravet syndrome	Discharged
21	Endotracheal aspirate	6	S ≤ 0.5	R ≥ 16	R ≥ 64	R ≥ 8	62	M	Pneumonia	Gas gangrene	Expired
22	Sputum	6	S ≤ 0.5	R ≥ 16	R ≥ 64	R ≥ 8	45	F	Pneumonia	Systemic sclerosis, ovarian cancer	Expired
23	Sputum	6	S ≤ 0.5	R ≥ 16	R ≥ 64	R ≥ 8	71	M	Pneumonia	Esophageal cancer	Discharged
24	Sputum	6	S ≤ 0.5	R ≥ 16	R ≥ 64	I 4	70	M	Pneumonia	Esophageal cancer	Expired
25	Sputum	6	S ≤ 0.5	R ≥ 16	R ≥ 64	R ≥ 8	43	M	Pneumonia	Cerebral palsy, AV block	Discharged
26	Endotracheal aspirate	6	S ≤ 0.5	R ≥ 16	R ≥ 64	R ≥ 8	75	M	Mediastinitis	Cerebrovascular attack, peptic ulcer	Expired
27	Endotracheal aspirate	6	S ≤ 0.5	R ≥ 16	R ≥ 64	I 4	69	F	None	Hypoxic brain damage	Discharged
28	Sputum	6	S ≤ 0.5	R ≥ 16	R ≥ 64	R ≥ 8	9	F	Pneumonia, pleural effusion	Encephalitis	Inpatient
29^**	Sputum	6	S ≤ 0.5	R ≥ 16	R ≥ 64	R ≥ 8	71	M	Pneumonia	Urinary tract infection, osteomyelitis, invasive aspergillosis	Discharged
30	Sputum	4	R ≥ 16	R ≥ 16	R ≥ 64	R ≥ 8	66	M	Pneumonia	Anaplastic astrocytoma, atrial septal defect	Discharged
31^***	—	—	S ≤ 0.5	R ≥ 16	R ≥ 64	R ≥ 8	—	—	—	—	—
32^***	—	—	S ≤ 0.5	R ≥ 16	R ≥ 64	R ≥ 8	—	—	—	—	—

Sputum grade is assessed based on a modified Washington and Murray score system.
^**Isolates numbers 12 and 29 were collected from the same patient at different times during hospitalization.
^***Environment surveillance specimens (monitor cable line between beds).
MIC, minimal inhibitory concentration; COL, colistin; IPM, imipenem; CTX, cefotaxime; LEV, levofloxacin; S, susceptible; R, resistant; I, intermediate.