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BioMed Research International
Volume 2015, Article ID 535431, 6 pages
http://dx.doi.org/10.1155/2015/535431
Clinical Study

Influence of Preoperative Peripheral Parenteral Nutrition with Micronutrients after Colorectal Cancer Patients

1Department of Nutrition, Tainan Sin-Lau Hospital, No. 57, Sec. 1, Dongmen Road, Tainan 70142, Taiwan
2Department of Surgery, Tainan Sin-Lau Hospital, No. 57, Sec. 1, Dongmen Road, Tainan 70142, Taiwan
3Department of Medical Laboratory Science and Biotechnology, Kaohsiung Medical University, No. 100, Tzyou 1st Road, Kaohsiung 807, Taiwan
4Department of Nutrition and Dietetics, Kaohsiung Medical University Hospital, No. 100, Tzyou 1st Road, Kaohsiung 807, Taiwan
5Department of Nursing, Tainan Sin-Lau Hospital, No. 57, Sec. 1, Dongmen Road, Tainan 70142, Taiwan
6Department of Life Sciences, College of Bioscience and Biotechnology, National Cheng Kung University, No. 1, University Road, Tainan 701, Taiwan

Received 28 February 2015; Accepted 16 April 2015

Academic Editor: Sung-Hoon Kim

Copyright © 2015 Ming-Yi Liu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. The inflammatory reactions are stronger after surgery of malnourished preoperative patients. Many studies have shown vitamin and trace element deficiencies appear to affect the functioning of immune cells. Enteral nutrition is often inadequate for malnourished patients. Therefore, total parenteral nutrition (TPN) is considered an effective method for providing preoperative nutritional support. TPN needs a central vein catheter, and there are more risks associated with TPN. However, peripheral parenteral nutrition (PPN) often does not provide enough energy or nutrients. Purpose. This study investigated the inflammatory response and prognosis for patients receiving a modified form of PPN with added fat emulsion infusion, multiple vitamins (MTV), and trace elements (TE) to assess the feasibility of preoperative nutritional support. Methods. A cross-sectional design was used to compare the influence of PPN with or without adding MTV and TE on malnourished abdominal surgery patients. Results. Both preoperative groups received equal calories and protein, but due to the lack of micronutrients, patients in preoperative Group B exhibited higher inflammation, lower serum albumin levels, and higher anastomotic leak rates and also required prolonged hospital stays. Conclusion. Malnourished patients who receive micronutrient supplementation preoperatively have lower postoperative inflammatory responses and better prognoses. PPN with added fat emulsion, MTV, and TE provides valid and effective preoperative nutritional support.