Neonatal Death and Heart Failure in Mouse with Transgenic HSP60 Expression

Figure 4

Histology of the neonatal heart and lung. Top, H&E staining of the neonatal heart of H⁺/C⁺ mouse compared with that of H⁺/C⁻ mouse, showing hemorrhage, necrosis, and degenerated cardiac muscles in H⁺/C⁺ mouse heart. Bottom, the lung of H⁺/C⁺ mouse shows signs of hemorrhage, liquid congestion, and tissue necrosis. The alveolar lung structures appeared to have developed normally but poorly inflated. Scale bar = 100 μm.