Research Article

Biological Niches within Human Calcified Aortic Valves: Towards Understanding of the Pathological Biomineralization Process

Table 1

Patients characteristics.

CharacteristicOverall 
= 36
Tricuspid aortic valve 
= 29
Bicuspid aortic valve 
= 3
Mitral valve 
= 4

Age, y72.4 ± 1074.5 ± 7.855 ± 1569 ± 9
Males, 25 (69.4%)20 (69%)3 (100%)2 (50%)
BMI, Kg/cm225.1 ± 5.525.5 ± 622.2 ± 3.722.4 ± 2
BSA, m21.8 ± 0.21.8 ± 0.21.7 ± 0.11.7 ± 0.2
Peak gradient, mmHg71.2 ± 20.570.5 ± 2388.4 ± 189 ± 3.5
Mean gradient, mmHg55.8 ± 16.253.4 ± 18.358.8 ± 146 ± 3.4
Associated CAD13 (36%)13 (44.8%)0 (0%)0 (0%)
Dialysis0 (0%)0 (%)0 (0%)0 (0%)
Osteoporosis22 (61%)21 (72%)0 (0%)1 (25%)

BMI: body mass index; BSA: body surface area; CAD: coronary artery disease.