Research Article
The Correlation between miRNA and Lymph Node Metastasis in Gastric Cancer
Table 2
The clinicopathological characteristics between gastric cancer patients according to the expression of miR-1207-5p.
| | Unchanged miR-1207-5p | Downregulated miR-1207-5p | Upregulated miR-1207-5p | value | | | | | | (%) | (%) | (%) |
| Age (y/o) | | | | 0.891 | <65 | 9 (33.3) | 1 (50) | 6 (35.3) | | ≧65 | 18 (66.7) | 1 (50) | 11 (64.7) | | Gender | | | | 0.890 | M/F | 16/11 | 1/1 | 11/6 | | Tumor size (cm) | | | | 0.986 | <5 | 14 (51.9) | 1 (50) | 10 (58.8) | | ≧5 | 13 (48.1) | 1 (50) | 7 (41.2) | | Tumor location | | | | 0.421 | Upper third stomach | 4 (14.8) | 0 | 4 (23.5) | | Middle third stomach | 10 (37) | 2 (100) | 7 (41.2) | | Lower third stomach | 13 (48.1) | 0 | 6 (35.3) | | Lauren’s classification | | | | 0.061 | Intestinal type | 14 (51.9) | 0 | 13 (76.5) | | Diffuse type | 13 (48.1) | 2 (100) | 4 (23.5) | | Cell differentiation | | | | 0.100 | Poor | 14 (51.9) | 2 (100) | 5 (29.4) | | Moderate/well | 13 (48.1) | 0 | 12 (70.6) | | Stromal reaction type | | | | 0.013 | Medullary | 1 (3.7) | 1 (50) | 5 (29.4) | | Intermediate | 21 (77.8) | 0 | 12 (70.6) | | Scirrhous | 5 (18.5) | 1 (50) | 0 | | Lymphovascular invasion | | | | 0.006 | Absence | 9 (33.3) | 1 (50) | 13 (76.5) | | Presence | 18 (66.7) | 1 (50) | 4 (23.5) | | Pathological T categories | | | | 0.005 | T1 | 1 (3.7) | 1 (50) | 10 (58.8) | | T2 | 9 (33.3) | 0 | 3 (17.6) | | T3 | 14 (51.9) | 1 (50) | 4 (23.5) | | T4 | 3 (11.1) | 0 | 0 | | Pathological N categories | | | | 0.005 | N0 | 7 (25.9) | 1 (50) | 14 (82.4) | | N1 | 7 (25.9) | 0 | 0 | | N2 | 6 (22.3) | 0 | 2 (11.8) | | N3 | 7 (25.9) | 1 (50) | 1 (5.9) | | Pathological TNM stage | | | | 0.002 | I | 6 (22.2) | 1 (50) | 12 (70.6) | | II | 10 (37) | 0 | 4 (23.5) | | III | 6 (22.2) | 0 | 1 (15.2) | | IV | 5 (18.6) | 1 (50) | 0 | |
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