Serum Vitamin D and Pyridinoline Cross-Linked Carboxyterminal Telopeptide of Type I Collagen in Patients with Ankylosing Spondylitis
Table 2
Comparison of biochemical index and BMD in different groups (AS patients were divided into groups according to different clinical factor).
AS group
25(OH)D (nmol/L)
ICTP (ug/L)
Lumbar spine BMD (-score)
Hip BMD (-score)
Gender
Male
127
56.81 ± 22.79
6.07 ± 4.05
−1.64 ± 1.24
−0.90 ± 0.94
Female
23
64.08 ± 31.90
3.84 ± 1.96**
−1.51 ± 1.69
−1.01 ± 0.86
Clinical type
AAS
134
58.90 ± 25.19
5.27 ± 3.65
−1.58 ± 1.35
−0.88 ± 0.90
JAS
16
49.78 ± 14.81
9.52 ± 3.79**
−1.96 ± 1.03
−1.21 ± 1.08
Disease duration
>4 y
100
58.44 ± 27.58
5.78 ± 4.05
−1.54 ± 1.36
−1.02 ± 0.91
≦4 y
50
56.88 ± 16.56
5.62 ± 3.55
−1.79 ± 1.23
−0.71 ± 0.93
HLA-B27
Positive
129
56.98 ± 25.25
5.95 ± 4.03
−1.60 ± 1.34
−0.93 ± 0.93
Negative
21
63.72 ± 17.96
4.32 ± 2.37
−1.78 ± 1.36
−0.82 ± 0.92
CRP (mg/L)
>6
109
58.00 ± 21.65
5.94 ± 3.96
−1.71 ± 1.40
−0.99 ± 0.94
≦6
41
57.72 ± 30.92
5.16 ± 3.66
−1.37 ± 1.03
−0.72 ± 0.88
25(OH)D (nmol/L)
>50
91
4.75 ± 2.23
−1.53 ± 1.35
−0.75 ± 0.86
≦50
59
7.23 ± 5.21**
−1.77 ± 1.26
−1.18 ± 0.97**
BASDAI
>4
29
50.93 ± 17.25
6.70 ± 5.47
−2.21 ± 1.42
−1.31 ± 0.86
≦4
121
59.60 ± 25.62
5.49 ± 3.38
−1.51 ± 1.27*
−0.82 ± 0.92*
Note: independent-sample -test was used between groups. Values are in means ± SD. C-reactive protein (CRP), bone mineral density (BMD), Bath AS Disease Activity Index (BASDAI), 25-hydroxyvitamin D (25(OH)D); pyridinoline cross-linked carboxyterminal telopeptide of type I collagen (ICTP). The comparison between the two groups. Statistically significant correlation . Statistically significant correlation .
