Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2015, Article ID 569052, 8 pages
http://dx.doi.org/10.1155/2015/569052
Clinical Study

Acoustic Coordinated Reset Neuromodulation in a Real Life Patient Population with Chronic Tonal Tinnitus

1Institute of Neuroscience and Medicine-Neuromodulation (INM-7), Jülich Research Center, 52425 Jülich, Germany
2CERES GmbH Evaluation & Research, 79539 Lörrach, Germany
3The Tinnitus Clinic Inc., London W1G 6AX, UK
4Tinnitus Zentrum Promenadeplatz, 80333 München, Germany
5Ear, Nose and Throat (ENT) Center, 40667 Meerbusch, Germany
6Ear, Nose and Throat (ENT) Clinic Hamm-Ahlen-Oelde, 59302 Oelde, Germany
7Department of Psychiatry and Psychotherapy, University of Regensburg, 93053 Regensburg, Germany
8Department of Neurosurgery, Stanford University, Stanford, CA 94305, USA
9Department of Neuromodulation, University of Cologne, 50923 Cologne, Germany

Received 3 November 2014; Accepted 11 January 2015

Academic Editor: Aage R. Møller

Copyright © 2015 Christian Hauptmann et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. J. Eggermont and L. E. Roberts, “The neuroscience of tinnitus,” Trends in Neurosciences, vol. 27, no. 11, pp. 676–682, 2004. View at Publisher · View at Google Scholar · View at Scopus
  2. A. Axelsson and A. Ringdahl, “Tinnitus—a study of its prevalence and characteristics,” British Journal of Audiology, vol. 23, no. 1, pp. 53–62, 1989. View at Publisher · View at Google Scholar · View at Scopus
  3. B. Langguth, “Tinnitus: the end of therapeutic nihilism,” The Lancet, vol. 379, no. 9830, pp. 1926–1928, 2012. View at Publisher · View at Google Scholar · View at Scopus
  4. N. Weisz, S. Moratti, M. Meinzer, K. Dohrmann, and T. Elbert, “Tinnitus perception and distress is related to abnormal spontaneous brain activity as measured by magnetoencephalography,” PLoS Medicine, vol. 2, no. 6, article e153, 2005. View at Publisher · View at Google Scholar · View at Scopus
  5. K. Dohrmann, T. Elbert, W. Schlee, and N. Weisz, “Tuning the tinnitus percept by modification of synchronous brain activity,” Restorative Neurology and Neuroscience, vol. 25, no. 3-4, pp. 371–378, 2007. View at Google Scholar · View at Scopus
  6. N. Kahlbrock and N. Weisz, “Transient reduction of tinnitus intensity is marked by concomitant reductions of delta band power,” BMC Biology, vol. 6, article 4, 2008. View at Publisher · View at Google Scholar · View at Scopus
  7. M. Ortmann, N. Müller, W. Schlee, and N. Weisz, “Rapid increases of gamma power in the auditory cortex following noise trauma in humans,” European Journal of Neuroscience, vol. 33, no. 3, pp. 568–575, 2011. View at Publisher · View at Google Scholar · View at Scopus
  8. P. A. Tass, I. Adamchic, H. J. Freund, T. von Stackelberg, and C. Hauptmann, “Counteracting tinnitus by acoustic coordinated reset neuromodulation,” Restorative Neurology and Neuroscience, vol. 30, no. 2, pp. 137–159, 2012. View at Publisher · View at Google Scholar · View at Scopus
  9. I. Adamchic, T. Toth, C. Hauptmann, and P. A. Tass, “Reversing pathologically increased EEG power by acoustic coordinated reset neuromodulation,” Human Brain Mapping, vol. 35, no. 5, pp. 2099–2118, 2014. View at Publisher · View at Google Scholar · View at Scopus
  10. J. J. Eggermont and P. A. Tass, “Maladaptive neural synchrony in tinnitus: origin and restoration,” Frontiers in Neurology. In press.
  11. W. Schlee, N. Weisz, O. Bertrand, T. Hartmann, and T. Elbert, “Using auditory steady state responses to outline the functional connectivity in the tinnitus brain,” PLoS ONE, vol. 3, no. 11, Article ID e3720, 2008. View at Publisher · View at Google Scholar · View at Scopus
  12. W. Schlee, T. Hartmann, B. Langguth, and N. Weisz, “Abnormal resting-state cortical coupling in chronic tinnitus,” BMC Neuroscience, vol. 10, article 11, 2009. View at Publisher · View at Google Scholar · View at Scopus
  13. D. De Ridder, A. B. Elgoyhen, R. Romo, and B. Langguth, “Phantom percepts: tinnitus and pain as persisting aversive memory networks,” Proceedings of the National Academy of Sciences of the United States of America, vol. 108, no. 20, pp. 8075–8080, 2011. View at Publisher · View at Google Scholar · View at Scopus
  14. A. N. Silchenko, I. Adamchic, C. Hauptmann, and P. A. Tass, “Impact of acoustic coordinated reset neuromodulation on effective connectivity in a neural network of phantom sound,” NeuroImage, vol. 77, pp. 133–147, 2013. View at Publisher · View at Google Scholar · View at Scopus
  15. P. Adjamian, M. Sereda, O. Zobay, D. A. Hall, and A. R. Palmer, “Neuromagnetic indicators of tinnitus and tinnitus masking in patients with and without hearing loss,” Journal of the Association for Research in Otolaryngology, vol. 13, no. 5, pp. 715–731, 2012. View at Publisher · View at Google Scholar · View at Scopus
  16. R. Llinás, F. J. Urbano, E. Leznik, R. R. Ramírez, and H. J. F. Van Marle, “Rhythmic and dysrhythmic thalamocortical dynamics: GABA systems and the edge effect,” Trends in Neurosciences, vol. 28, no. 6, pp. 325–333, 2005. View at Publisher · View at Google Scholar · View at Scopus
  17. D. E. Tunkel, C. A. Bauer, and G. H. Sun, “Clinical practice guideline: tinnitus,” Otolaryngology—Head and Neck Surgery, vol. 151, no. 2, supplement, pp. S1–S40, 2014. View at Publisher · View at Google Scholar
  18. P. Martinez-Devesa, A. Waddell, R. Perera, and M. Theodoulou, “Cognitive behavioural therapy for tinnitus,” Cochrane Database of Systematic Reviews, no. 8, Article ID CD005233, 2010. View at Google Scholar
  19. D. J. Hoare, M. Edmondson-Jones, M. Sereda, M. A. Akeroyd, and D. Hall, “Amplification with hearing aids for patients with tinnitus and co-existing hearing loss,” The Cochrane Database of Systematic Reviews, vol. 1, Article ID CD010151, 2014. View at Publisher · View at Google Scholar
  20. J. Hobson, E. Chisholm, and A. El Refaie, “Sound therapy (masking) in the management of tinnitus in adults,” Cochrane Database of Systematic Reviews, no. 11, Article ID CD006371, 2012. View at Google Scholar
  21. J. S. Phillips and D. McFerran, “Tinnitus retraining therapy (TRT) for tinnitus,” Cochrane Database of Systematic Reviews, vol. 3, Article ID CD007330, 2010. View at Google Scholar · View at Scopus
  22. M. P. Hilton, E. F. Zimmermann, and W. T. Hunt, “Ginkgo biloba for tinnitus,” The Cochrane Database of Systematic Reviews, vol. 3, Article ID CD003852, 2013. View at Publisher · View at Google Scholar
  23. P. Baldo, C. Doree, P. Molin, D. McFerran, and S. Cecco, “Antidepressants for patients with tinnitus,” Cochrane Database of Systematic Reviews, vol. 9, Article ID CD003853, 2012. View at Google Scholar · View at Scopus
  24. C. E. Hoekstra, S. P. Rynja, G. A. van Zanten, and M. M. Rovers, “Anticonvulsants for tinnitus,” Cochrane Database of Systematic Reviews, no. 7, Article ID CD007960, 2011. View at Google Scholar · View at Scopus
  25. M. H. Bennett, T. Kertesz, M. Perleth, P. Yeung, and J. P. Lehm, “Hyperbaric oxygen for idiopathic sudden sensorineural hearing loss and tinnitus,” Cochrane Database of Systematic Reviews, vol. 10, Article ID CD004739, 2012. View at Google Scholar · View at Scopus
  26. J. I. Kim, J. Y. Choi, D. H. Lee, T. Y. Choi, M. S. Lee, and E. Ernst, “Acupuncture for the treatment of tinnitus: a systematic review of randomized clinical trials,” BMC Complementary and Alternative Medicine, vol. 12, article 97, 2012. View at Publisher · View at Google Scholar · View at Scopus
  27. B. Langguth and D. de Ridder, “Tinnitus: therapeutic use of superficial brain stimulation,” Handbook of Clinical Neurology, vol. 116, pp. 441–467, 2013. View at Publisher · View at Google Scholar · View at Scopus
  28. P. A. Tass, “A model of desynchronizing deep brain stimulation with a demand-controlled coordinated reset of neural subpopulations,” Biological Cybernetics, vol. 89, no. 2, pp. 81–88, 2003. View at Publisher · View at Google Scholar · View at Scopus
  29. P. A. Tass and M. Majtanik, “Long-term anti-kindling effects of desynchronizing brain stimulation: a theoretical study,” Biological Cybernetics, vol. 94, no. 1, pp. 58–66, 2006. View at Publisher · View at Google Scholar · View at MathSciNet · View at Scopus
  30. P. A. Tass and O. V. Popovych, “Unlearning tinnitus-related cerebral synchrony with acoustic coordinated reset stimulation: theoretical concept and modelling,” Biological Cybernetics, vol. 106, no. 1, pp. 27–36, 2012. View at Publisher · View at Google Scholar · View at Scopus
  31. I. Adamchic, B. Langguth, C. Hauptmann, and P. A. Tass, “Abnormal brain activity and cross-frequency coupling in the tinnitus network,” Frontiers in Neuroscience, vol. 8, article 284, 2014. View at Google Scholar
  32. I. Adamchic, B. Langguth, C. Hauptmann, and P. A. Tass, “Psychometric evaluation of visual analog scale for the assessment of chronic tinnitus,” The American Journal of Audiology, vol. 21, no. 2, pp. 215–225, 2012. View at Publisher · View at Google Scholar · View at Scopus
  33. I. Adamchic, P. A. Tass, B. Langguth et al., “Linking the tinnitus questionnaire and the subjective clinical global impression: which differences are clinically important?” Health and Quality of Life Outcomes, vol. 10, article 79, 2012. View at Publisher · View at Google Scholar · View at Scopus
  34. R. Görtelmeyer, J. Schmidt, M. Suckfüll et al., “Assessment of tinnitus-related impairments and disabilities using the German THI-12: sensitivity and stability of the scale over time,” International Journal of Audiology, vol. 50, no. 8, pp. 523–529, 2011. View at Publisher · View at Google Scholar · View at Scopus
  35. B. Langguth, R. Goodey, A. Azevedo et al., “Consensus for tinnitus patient assessment and treatment outcome measurement: tinnitus Research Initiative meeting, Regensburg, July 2006,” Progress in Brain Research, vol. 166, pp. 525–536, 2007. View at Publisher · View at Google Scholar · View at Scopus
  36. P. M. Kreuzer, M. Landgrebe, V. Vielsmeier, T. Kleinjung, D. de Ridder, and B. Langguth, “Trauma-associated tinnitus,” Journal of Head Trauma Rehabilitation, vol. 29, no. 5, pp. 432–442, 2014. View at Publisher · View at Google Scholar · View at Scopus
  37. B. Lysyansky, O. V. Popovych, and P. A. Tass, “Desynchronizing anti-resonance effect of m: N ON–OFF coordinated reset stimulation,” Journal of Neural Engineering, vol. 8, no. 3, Article ID 036019, 2011. View at Publisher · View at Google Scholar · View at Scopus
  38. U. S. Bankstahl, E. P. Elkin, A. Gebauer, and R. Görtelmeyer, “Validation of the THI-12 questionnaire for international use in assessing tinnitus: A multi-centre, prospective, observational study,” International Journal of Audiology, vol. 51, no. 9, pp. 671–677, 2012. View at Publisher · View at Google Scholar · View at Scopus
  39. F. Zeman, M. Koller, M. Schecklmann et al., “Tinnitus assessment by means of standardized self-report questionnaires: psychometric properties of the Tinnitus Questionnaire (TQ), the Tinnitus Handicap Inventory (THI), and their short versions in an international and multi-lingual sample,” Health and Quality of Life Outcomes, vol. 10, article 128, 2012. View at Publisher · View at Google Scholar · View at Scopus
  40. R. F. F. Cima, I. H. Maes, M. A. Joore et al., “Specialised treatment based on cognitive behaviour therapy versus usual care for tinnitus: a randomised controlled trial,” The Lancet, vol. 379, no. 9830, pp. 1951–1959, 2012. View at Publisher · View at Google Scholar · View at Scopus