Preparation, Optimization, and Screening of the Effect of Processing Variables on Agar Nanospheres Loaded with Bupropion HCl by a D-Optimal Design

Table 3

Summary of results of regression analysis for responses , , , and .

Model		Adjusted	Predicted	Mean	S.D.	C.V.%
(particle size)	0.2522	0.1454	−0.0439	564.30	121.77	21.58
(Zeta potential)	0.4004	0.3147	0.1353	−29.56	3.14	10.63
(drug loading efficiency)	0.6135	0.5783	0.5034	34.59	5.11	14.78
(RE300%)	0.5559	0.3731	0.0260	79.96	6.16	7.71