Research Article
Preparation, Optimization, and Screening of the Effect of Processing Variables on Agar Nanospheres Loaded with Bupropion HCl by a D-Optimal Design
Table 3
Summary of results of regression analysis for responses
,
,
, and
.
| Model | | Adjusted | Predicted | Mean | S.D. | C.V.% |
| (particle size) | 0.2522 | 0.1454 | ā0.0439 | 564.30 | 121.77 | 21.58 | (Zeta potential) | 0.4004 | 0.3147 | 0.1353 | ā29.56 | 3.14 | 10.63 | (drug loading efficiency) | 0.6135 | 0.5783 | 0.5034 | 34.59 | 5.11 | 14.78 | (RE300%) | 0.5559 | 0.3731 | 0.0260 | 79.96 | 6.16 | 7.71 |
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