Research Article

Preparation, Optimization, and Screening of the Effect of Processing Variables on Agar Nanospheres Loaded with Bupropion HCl by a D-Optimal Design

Table 5

The results of mucoadhesion measurement of the optimized agar nanospheres in different fluids and in different concentrations of hydroxypropyl -cyclodextrin (in acetate buffer).

Acetate bufferSimulated lung fluid HPCD 0%HPCD 0.5%HPCD 1%

99.5%92.86%99.4%99.5%99.3%