Preparation, Optimization, and Screening of the Effect of Processing Variables on Agar Nanospheres Loaded with Bupropion HCl by a D-Optimal Design

Table 6

The results of measuring the particle size, zeta potential, and drug content of the optimum formulation measured in the simulated lung fluid [16] immediately and 9 hours after preparation.

Particle size (nm)		Zeta potential (mV)
At zero time	After 9 hrs	At zero time	After 9 hrs
553 ± 32	600 ± 40	−11.6	−10.6