Low-Rank and Sparse Matrix Decomposition for Genetic Interaction Data

Figure 5

Global view of the genetic cross talks between different RNA-related processes (GO BP FAT). Green and red represent a statistically significant enrichment of negative (genetic interaction score ) and positive (genetic interaction score ) interactions, respectively, whereas yellow corresponds to cases where there are roughly equal numbers of positive and negative genetic interactions. Nodes (balls) correspond to distinct functional processes; edges (lines) represent how the processes are genetically connected. The square heat maps represent scores of interactions within one process, and the rectangle heat maps represent scores of interactions between two processes.