A New Approach Using Manganese-Enhanced MRI to Diagnose Acute Mesenteric Ischemia in a Rabbit Model: Initial Experience

Figure 2

Effect of altering the dose of infused Mn²⁺ on small intestinal wall relaxivity. (a) The dose-dependent curve for different dose of MnCl₂ administration. -axis showed the total dose of infused Mn²⁺ normalized to rabbit BW. -axis showed the change of relaxation rate, . As a function of dose, a linear dose-uptake region was noted along with a plateau region above 15 nmol/g BW. The linear fit was shown with total Mn²⁺ infusion dose, , in nmol/g BW. Data are presented as the mean ± SEM of . (b) Temporal Mn²⁺ washout curve. -axis showed the experimental time course after Mn²⁺ infusion. -axis showed the difference in the change of relaxation rate, .

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