Decreased Pulmonary Function in School Children in Western Japan after Exposures to Asian Desert Dusts and Its Association with Interleukin-8

Figure 5

IL-8 transcriptional activity measured using an IL-8 luciferase assay in a stable THP-1-derived IL-8 reporter cell line. Cells were treated with solvent only (, negative control), LPS (, 100 pg/mL, positive control), LPS (, 100 ng/mL, positive control), and ADS airborne particles collected on April 23 and 24, 2012 (, 1 mg/mL), March 8 to 10, 2013 (, 1 mg/mL), and March 19 and 20, 2013 (, 1 mg/mL). ^* versus LPS at 100 pg/mL, ^** versus LPS at 100 pg/mL, and versus ADS airborne particles from April 23 to April 24, 2012.