Sublingual Immunotherapy with a Five-Grass Pollen Tablet in Adult Patients with Allergic Rhinitis: An Open, Prospective, Noninterventional, Multicenter Study
Table 2
Time course of adverse drug reactions (ADRs) after the first intake of the five-grass pollen tablet.
MedDRA system organ class and low-level term (LLT)
Time lag between first intake and onset median (range) [minutes]
Duration median (range) [minutes]
Gastrointestinal disorders
5 (0–570)
16 (1 min–63.5 hours)
Tingling mouth
5 (0–20)
14 (2–180)
Oral pruritus
5 (0–60)
15 (2–180)
Respiratory, thoracic, and mediastinal disorders
5 (0–645)
15.5 (2–360)
Throat irritation
5 (0–645)
10 (2–75)
MedDRA: Medical Dictionary for Regulatory Activities, Version 11.1.
