Exploring the Link between the Components of Metabolic Syndrome and the Risk of Depression

Table 2

Regression coefficients of number of metabolic syndromes for PHQ-9 score predicted.

Variables	Insulin resistance (HOMA-IR ≥ 2.5)						Noninsulin resistance (HOMA-IR < 2.5)
	Model 1		Model 2		Model 3		Model 1		Model 2		Model 3
	(95% CI)	value	(95% CI)	value	β; (95% CI)	value	(95% CI)	value	(95% CI)	value	(95% CI)	value
Number of MetS components
1	0.972; (−0.5891, 2.533)	0.222	0.788; (−0.799, 2.376)	0.33	0.773; (−0.822, 2.367)	0.342	0.628; (−0.179, 1.435)	0.127	0.622; (−0.216, 1.461)	0.146	0.578; (−0.266, 1.422)	0.179
2	2.102; (0.586, 3.618)	0.007	1.788; (0.204, 3.372)	0.027	1.803; (0.23, 3.394)	0.026	0.512; (−0.425, 1.448)	0.284	0.395; (−0.629, 1.420)	0.449	0.205; (−0.861, 1.272)	0.705
3	1.755; (0.206, 3.304)	0.026	1.405; (−0.227, 3.037)	0.092	1.396; (−0.247, 3.038)	0.096	0.581; (−0.926, 2.089)	0.449	0.312; (−1.32, 1.944)	0.708	0.051; (−1.623, 1.725)	0.952
4	2.477; (0.88, 4.153)	0.004	2.153; (0.392, 3.914)	0.017	2.081; (0.289, 3.873)	0.023	0.143; (−2.658, 2.944)	0.920	0.065; (−2.775, 2.905)	0.964	−0.109; (−2.962, 2.743)	0.940
5	3.444; (1.145, 5.744)	0.003	3.202; (0.816, 5.588)	0.009	3.048; (0.638, 5.459)	0.013	3.204; (−2.824, 9.231)	0.297	2.519; (−2.321, 2.19)	0.410	1.886; (−4.239, 8.010)	0.546
for trend	0.001		0.004		0.008		0.236		0.495		0.784

Model 1 = age, sex, race/ethnicity.
Model 2 = Model 1 + (BMI, alcohol drinking, smoking, coronary heart disease, stroke, and vigorous working activity).
Model 3 = Model 2 + (serum C-reactive protein, serum total bilirubin, serum uric acid, and HOMA-IR).