Magnetic Bead-Based Serum Peptidome Profiling in Patients with Gestational Diabetes Mellitus

Table 2

(a) Extremely significant ( < 0.01) / values distinguishing GDMs from controls. (b) Significant ( < 0.05) / values distinguishing GDM1 from GDM2. (c) Sequences of the differentially expressed peptides.

(a)

Mean / value	value	Tendency^b
4418.9	0.005	↑
2219.7	0.003	↓
2211.5	0.006	↓
1533.4	0.007	↓

Tendency ↑: the intensity of / values of GDMs is higher than the controls; ↓: the intensity of GDMs is lower than the controls.

(b)

Mean / value	value	Tendency^c
4418.9	0.014	↑
2211.5	0.029	↓
1533.4	0.022	↓

Tendency ↑: the intensity of / values of GDM2 was higher than the GDM1; ↓: the intensity was lower in GDM2.

(c)

Mean / value	Peptide sequence	Identified peptide
4418.9	—	Unknown peptide
2219.7	A.MSTYTGIFTDQVLSVLKGEE. -	Apolipoprotein C II precursor
2211.5	Y.KMADEAGSEADHEGTHSTKRG.H	Isoform 1 of fibrinogen alpha chain precursor
1533.4	R.RPHFFFPKSRIV.R	Clusterin precursor