In Vivo MicroCT Monitoring of Osteomyelitis in a Rat Model

Figure 3

Microphotographs of histological sections. Giemsa-Eosin stained overview of (a) sterile screw showing direct osseointegration of the screw without any signs of osteolysis and (b) an inoculated screw showing loosening, pronounced osteolysis, and massive purulent inflammation with formation of microabscesses (red arrows) partly with a small infected dead bone chip (red box). (c) Magnification of red box showing microabscess around a dead bone chip (stained purple, red box). (d) Magnification of the infected bone chip and Brown-Brenn positive coccoid bacteria.

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