Research Article

Blood or Urine IP-10 Cannot Discriminate between Active Tuberculosis and Respiratory Diseases Different from Tuberculosis in Children

Table 2

IP-10 values in blood and urine of children with or without active TB stratified by HIV infection. Healthy adult donors were included as controls.

HIV-uninfected childrenHIV-infected childrenHealthy adult donors
Culture-confirmedHighly probableProbableTotal active TBRespiratory diseasesCulture-confirmedHighly probableProbableTotal active TBRespiratory diseases

7751961103131833

Blood IP-10
Median (IQR)
563.9 
(381.9–926.6)
432.2 
(234.4–596.8)
213.9 
(95.9–349.2)
381.9 
(213.9–596.8)
204.1 
(126.4–426.6)
611.2 
(249.7–688.9)
396.9 
(383.6–673.6)
609.8 
(317.6–671.5)
525.9 
(319.7–680.6)
103.3 
(81.9–145.3)

Urine IP-10
Median (IQR)

(0–)

(0–)
0 
(0–)

(0–8)

(0–)

(0–)

(0–)

(0–)

(0–)

(0–)

TB: tuberculosis; IQR: interquartile range; HIV: Human Immunodeficiency Virus.