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BioMed Research International
Volume 2015, Article ID 591603, 8 pages
Research Article

Outcomes of Cryoballoon Ablation in High- and Low-Volume Atrial Fibrillation Ablation Centres: A Russian Pilot Survey

1Arrhythmia Department, Federal Almazov North-West Medical Research Centre, Saint Petersburg 197341, Russia
2Neuromodulation Unit, Federal Almazov North-West Medical Research Centre, Saint Petersburg 197341, Russia
3Center of Interventional Cardiology, State Research Institute of Circulation Pathology, Novosibirsk 630055, Russia
4National Research Center for Preventive Medicine, Moscow 101990, Russia
5Federal Center for Cardiovascular Surgery, Krasnoyarsk 660020, Russia
6Federal Center for Cardiovascular Surgery, Astrakhan 414011, Russia
7Electrophysiology Department, City Hospital #5, Nizhny Novgorod 603005, Russia
8Electrophysiology Department, Tyumen Cardiology Center, Tyumen 625026, Russia
9Electrophysiology Department, Research Institute of Cardiology, Saratov 410028, Russia
10Cardiovascular Surgery Department, City Hospital #12, Moscow 115516, Russia
11Department of Clinical Electrophysiology, Russian Cardiology Research and Production Center, Moscow 121552, Russia
12Tyumen Regional Hospital #1, Tyumen 625032, Russia
13Republican Clinical Hospital of the Republic of Tatarstan, Kazan 420064, Russia
14Botkin City Hospital, Moscow 125284, Russia
15Bakulev Scientific Center of Cardiovascular Surgery, Moscow 121552, Russia
16Institute of Heart and Vessels, Federal Almazov North-West Medical Research Centre, Saint Petersburg 197341, Russia

Received 18 August 2015; Accepted 27 October 2015

Academic Editor: Laurent Pison

Copyright © 2015 Evgeny N. Mikhaylov et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Purpose. The results of cryoballoon ablation (CBA) procedure have been mainly derived from studies conducted in experienced atrial fibrillation (AF) ablation centres. Here, we report on CBA efficacy and complications resulting from real practice of this procedure at both high- and low-volume centres. Methods. Among 62 Russian centres performing AF ablation, 15 (24%) used CBA technology for pulmonary vein isolation. The centres were asked to provide a detailed description of all CBA procedures performed and complications, if encountered. Results. Thirteen sites completed interviews on all CBAs in their centres (>95% of CBAs in Russia). Six sites were high-volume AF ablation (>100 AF cases/year) centres, and 7 were low-volume AF ablation. There was no statistical difference in arrhythmia-free rates between high- and low-volume centres (64.6 versus 60.8% at 6 months). Major complications developed in 1.5% of patients and were equally distributed between high- and low-volume centres. Minor procedure-related events were encountered in 8% of patients and were more prevalent in high-volume centres. Total event and vascular access site event rates were higher in women than in men. Conclusions. CBA has an acceptable efficacy profile in real practice. In less experienced AF ablation centres, the major complication rate is equal to that in high-volume centres.