Review Article

Receptor Binding Domain Based HIV Vaccines

Table 1

Each of the listed antibodies target in different sites, including CD4bs, V1, V2, and V3 loop, membrane-proximal region of gp41 (MPER).

ā€‰EpitopeAntibody

NAbsCD4bsVRC01, VRC-PG04, 3BNC117/60, HJ16, 3BC176/315, NIH45-46, b12, and 1F7
V1/V2-glycanPG9, PG16
V3-glycanPGT121, PGT125, PGT135, PGT 128, 447-52D, and B48E
Gp412F5, 4E10, Z13e1, and 10E8

Non-NabsCD4i17b, X5, E51, 48d, and 412d
V3 447-52D, 19b, and 14e