Clinical Features in Juvenile-Onset Ankylosing Spondylitis Patients Carrying Different B27 Subtypes
Table 2
Comparison of clinical features, Bath AS indices, and inflammatory markers in JAS patients with B27-negative and different B27 subtypes.
HLA-B27 subtype
Age (y)
Onset age (y)
Disease duration (y)
BASDAI (score)
BASFI (score)
ESR (mm/h)
CRP (mg/L)
HLA-B27-negative
18.09 ± 3.65 ()
14.09 ± 2.11 ()
4.01 ± 4.39 ()
2.05 ± 1.42 ()
1.55 (1.21, 3.43 ) ()
7.00 (4.00, 9.40) ()
1.10 (0.60, 5.00) ()
HLA-B*2704
21.79 ± 8.02 ()
13.54 ± 2.31 ()
8.25 ± 8.06 ()
4.22 ± 1.95* ()
3.00 (1.90, 5.20) ()
32.00 (14.00, 48.75)* ()
18.55 (5.9, 49.78)* ()
HLA-B*2705
18.36 ± 3.96 ()
13.55 ± 1.77 ()
4.82 ± 4.46 ()
3.61 ± 1.26 ()
1.6 (1.00, 4.20) ()
14.0 (7.00, 48.00)* ()
5.80 (1.45, 34.30) ()
HLA-B*2715
24.33 ± 6.43 ()
9.00 ± 4.00*#a ()
15.33 ± 4.16*a ()
3.28 ± 2.79 ()
1.125 (1.00, 1.25) ()
65.00 (4.00, 135.00)* ()
15.53 (1.50, 113.45) ()
Note: (1) data in the table was mean ± standard deviation or median (upper quartile, lower quartile); (2) * comparison between groups of different B27 subtypes and group of B27-negative, ; (3) # comparison between HLA-2715 and HLA-2704 group, ; (4) a comparison between HLA-2715 and HLA-2705 group, .