Research Article

Clinical Features in Juvenile-Onset Ankylosing Spondylitis Patients Carrying Different B27 Subtypes

Table 2

Comparison of clinical features, Bath AS indices, and inflammatory markers in JAS patients with B27-negative and different B27 subtypes.

HLA-B27
subtype
Age (y) Onset age (y)Disease duration (y)BASDAI
(score)
BASFI
(score)
ESR
(mm/h)
CRP
(mg/L)

HLA-B27-negative 18.09 ± 3.65
()
14.09 ± 2.11
()
4.01 ± 4.39
()
2.05 ± 1.42
()
1.55 (1.21, 3.43 )
()
7.00 (4.00, 9.40)
()
1.10 (0.60, 5.00)
()
HLA-B*270421.79 ± 8.02
()
13.54 ± 2.31
()
8.25 ± 8.06
()
4.22 ± 1.95*
()
3.00 (1.90, 5.20)
()
32.00 (14.00, 48.75)*
()
18.55 (5.9, 49.78)*
()
HLA-B*270518.36 ± 3.96
()
13.55 ± 1.77
()
4.82 ± 4.46
()
3.61 ± 1.26
()
1.6 (1.00, 4.20)
()
14.0 (7.00, 48.00)*
()
5.80 (1.45, 34.30)
()
HLA-B*271524.33 ± 6.43
()
9.00 ± 4.00*#a
()
15.33 ± 4.16*a
()
3.28 ± 2.79 
()
1.125 (1.00, 1.25)  
()
65.00 (4.00, 135.00)*
()
15.53 (1.50, 113.45)  
()

Note: (1) data in the table was mean ± standard deviation or median (upper quartile, lower quartile); (2) * comparison between groups of different B27 subtypes and group of B27-negative, ; (3) # comparison between HLA-2715 and HLA-2704 group, ; (4) a comparison between HLA-2715 and HLA-2705 group, .