Growth Pattern of Clear Cell Renal Cell Carcinoma in Patients with Delayed Surgical Intervention: Fast Growth Rate Correlates with High Grade and May Result in Poor Prognosis

Table 2

Growth rate for ccRCC: overall and correlation with clinicopathologic variables.

	LGR (cm/yr)	VGR (cm^3/yr)	VDT (days)
Overall growth per year, = 61
Median	0.61	7.49	561
Mean ± SD	0.86	20.96	667
Range	0.00–4.74	0.31–211.93	33–3321
Growth rates and clinicopathologic variables
Grade
1,	0.32 ± 0.06	6.10 ± 3.15	885.69 ± 169.00
2,	0.74 ± 0.11	12.14 ± 2.27	684.08 ± 107.79
3,	2.03 ± 0.50	73.79 ± 22.79	319.60 ± 87.29
value	<0.001^*	0.001^*	0.017^*
Age
	−0.061	0.001	−0.045
value	0.638	0.991	0.733
Initial size
	0.207	0.027	0.335
value	0.110	0.836	0.008^*
Sex
Men, = 48 (mean ± SD)	0.83 ± 0.14	20.15 ± 6.05	661.15 ± 91.29
Women, = 13 (mean ± SD)	1.00 ± 0.28	23.95 ± 6.47	690.00 ± 169.95
value	0.355	0.098	0.673

LGR: linear growth rate; VGR: volumetric growth rate; VDT: volume doubling time.
^*Statistically significant.