Growth Pattern of Clear Cell Renal Cell Carcinoma in Patients with Delayed Surgical Intervention: Fast Growth Rate Correlates with High Grade and May Result in Poor Prognosis

Table 4

Clinical and pathological characteristics of SRMs that progressed to metastasis after delayed treatment.

Cases	Sex	Age (years)	Grade	ITS (cm)	UTS (cm)	LGR (cm/year)	Duration of AS (months)	Surgical treatment	Time to metastasis after surgery	Site of metastasis	Outcome
1	Male	63	3	6.7	8.8	0.9	28	RN	9	Pleura and lung	Mortality at 57 mo. after surgery
2	Male	61	2	4.5	5.4	1.08	10	RN	16	Neck	Mortality at 24 mo. after surgery
3	Female	65	1	1.9	2.81	0.61	18	RN	14	Lung	Alive at 20 mo. after surgery
4	Male	58	3	0.1	8.0	4.74	20	RN	12	Brain	Mortality at 19 mo. after surgery
5	Female	59	2	3.6	7.0	1.28	32	PN	66	Head of pancreas	Alive at 101 mo. after surgery

SRMs: small renal masses; ITS: initial tumor size; UTS: ultimate tumor size; LGR: linear growth rate; RN: radical nephrectomy; PN: partial nephrectomy.