Mushroom β-Glucan May Immunomodulate the Tumor-Associated Macrophages in the Lewis Lung Carcinoma

Figure 2

Effect of Antrodia camphorata beta-glucan on the amount of gene expressions of IL-12, GM-CSF, and IFN-γ in the lungs. Normal mice were fed with either twice-distilled water or Antrodia camphorata beta-glucan daily and euthanized after 12 days. Lungs were then harvested (). RT-qPCR was used to analyze gene expressions of IL-12, GM-CSF, and IFN-γ in the lungs. β-actin was used as the reference gene. (a) Amount of IL-12 gene expression. (b) Amount of GM-CSF gene expression. (c) Amount of IFN-γ gene expression. PC: fed with twice-distilled water; group PB: fed with Antrodia camphorata beta-glucan.

(a) IL-12

(b) GM-CSF

(c) IFN-γ