Mushroom β-Glucan May Immunomodulate the Tumor-Associated Macrophages in the Lewis Lung Carcinoma

Figure 4

Effect of Antrodia camphorata beta-glucan on the percentages of macrophages and proportions of M1 and M2 macrophages. Normal mice were fed with distilled water or Antrodia camphorata beta-glucan daily and euthanized after 12 days. Lungs were then harvested (). Flow cytometer was used to analyze the percentages of M1 and M2 macrophages in the lungs. (a) Percentages of macrophages. (b) Percentages of M1 macrophages. (c) Percentages of M2 macrophages. ^*Group PC: fed with twice-distilled water; group PB: fed with Antrodia camphorata beta-glucan.

(a) Macrophage

(b) M1

(c) M2