Mushroom β-Glucan May Immunomodulate the Tumor-Associated Macrophages in the Lewis Lung Carcinoma

Figure 6

Effect of Antrodia camphorata beta-glucan on the gene expressions of IL-12, GM-CSF, and IFN-γ in the lungs of tumor-bearing mice. Tumor-bearing mice were fed with either twice-distilled water, celecoxib, Antrodia camphorata beta-glucan, or Ganoderma beta-glucan daily and euthanized after 12 days. Lungs were then harvested (). RT-qPCR was used to quantify the amount of gene expressions of IL-12, GM-CSF, and IFN-γ. TC: fed with twice-distilled water; group TM: fed with celecoxib; group TB: fed with Antrodia camphorata beta-glucan; group TX: fed with Ganoderma beta-glucan.

(a) IL-12

(b) GM-CSF

(c) IFN-γ