Mushroom β-Glucan May Immunomodulate the Tumor-Associated Macrophages in the Lewis Lung Carcinoma

Figure 8

Effect of Antrodia camphorata beta-glucan on the percentages of macrophages and proportions of M1 and M2 macrophages in the lungs of tumor-bearing mice. Tumor-bearing mice were fed with either twice-distilled water, celecoxib, Antrodia camphorata beta-glucan, or Ganoderma beta-glucan daily and euthanized after 12 days. Lungs were then harvested (). Flow cytometer was used to analyze the percentages of macrophages and proportions of M1 and M2 macrophages in the lungs. (a) Percentages of macrophages. (b) Percentages of M1 macrophages. (c) Percentages of M2 macrophages. ^*Group TC: fed with twice-distilled water; TM: fed with celecoxib; group TB: fed with Antrodia camphorata beta-glucan; group TX: fed with Ganoderma beta-glucan.