Research Article

Coexpression Pattern Analysis of NPM1-Associated Genes in Chronic Myelogenous Leukemia

Table 3

Mapping coexpressed gene pairs to annotated gene pairs from each GO term for cellular component.

GO termsFisher exact testCorrected value
a b c d value

Ribonucleoprotein complex271107107271<0.001<0.018
Ribosome629962<0.001<0.018
Cytosolic ribosome224422<0.001<0.018
Ribosomal subunit264426<0.001<0.018
Cytosol273127127273<0.001<0.018
Cytosolic part348834<0.001<0.018
Large ribosomal subunit141010140.1933.474
Intracellular  non-membrane-bounded organelle281157157281<0.001<0.018
Intracellular organelle part459265265459<0.001<0.018
Cytosolic large ribosomal subunit100010<0.001<0.018
Cytoplasmic part481273273481<0.001<0.018
Cytoplasm704416416704<0.001<0.018
Intracellular organelle819413413819<0.001<0.018
Nuclear part1387373138<0.001<0.018
Nuclear lumen1035757103<0.001<0.018
Intracellular organelle lumen1238080123<0.001<0.018
Spliceosome1177110.1592.862
Nucleolus41191941<0.001<0.018

GO: gene ontology. GO terms highlighted in bold text are significantly mapped. a: mapped CML-specific strongly coexpressed pairs. b: mapped CML-specific weakly coexpressed pairs. c: mapped normal-specific strongly coexpressed pairs. d: mapped normal-specific weakly coexpressed pairs.