Research Article
State of the Art on the Evidence Base in Cardiac Regenerative Therapy: Overview of 41 Systematic Reviews
Table 2
Bivariate and multivariable analysis for review quality, effect estimates, and scholarly citations.
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Only independent variables significantly () associated with the dependent variable of interest are reported, but all the following variables were tested: year of publication, authors, North American/European corresponding author, studies included, patients included, RCTs only, type of setting, BMSC therapy, patient-level design, random effects analysis, small study effect testing, subgroup analysis, metaregression, conflict of interests, and funding; †a multivariable linear regression model with backward stepwise selection ( for exit 0.10) was used, including in the model all variables significantly () associated with the dependent variable at bivariate analysis; A Measurement Tool to Assess Systematic Reviews (AMSTAR) score; BMSC = bone marrow-derived stem cell; LVEF = left ventricular ejection fraction; RCT = randomized clinical trial. |