Evolutionary Pattern and Regulation Analysis to Support Why Diversity Functions Existed within PPAR Gene Family Members

Table 1

Selection pressure analysis of amino acid sites in PPARs.

Model	ln	Parameters estimates
Model 0
-HOLI	−4720.995579
-HOLI	−2960.312353
-HOLI	−2719.120808
-ZnF_C4	−1050.374116
-ZnF_C4	−1033.465323
-ZnF_C4	−1276.57302
Model 1a
-HOLI	−4622.51301
		-HOLI	−2894.97063
-HOLI	−2689.49404
		-ZnF_C4	−1062.29037
-ZnF_C4	−1027.39487
		-ZnF_C4	−1276.57373
Model 2a
-HOLI	−4622.51301		196.96513
		-HOLI		−2894.97063		130.683442
-HOLI	−2689.49404				59.253532
		-ZnF_C4	−1044.04256			12.66312
-ZnF_C4	−1027.39487				12.140902
		-ZnF_C4	−1276.57302			0.000004

Note: selection pressure on amino acid sites of the inspection is based on the calculation of (ω), where is nonsynonymous coding sequences of each base mutation rate (nonsynonymous substitution rate) and is a synonymous mutation rate (synonymous substitution rate). When the ω > 1, the gene is by positive selection; ω = 1, no selection pressure; ω < 1, by purifying selection.