Research Article

Systematic Analysis of Endometrial Cancer-Associated Hub Proteins Based on Text Mining

Table 1

The 20 most significant EC-related genes based on text mining.

GeneDescriptionCount value

PGRProgesterone receptor3230
TP53Tumor protein p532960
MLH1mutL homolog 11500
PTENPhosphatase and tensin homolog1300
MSH2mutS homolog 21120
VEGFAVascular endothelial growth factor A820
ERBB2erb-b2 receptor tyrosine kinase 2 (HER2)770
MSH6mutS homolog 6 750
EGFREpidermal growth factor receptor680
MKI67Antigen identified by monoclonal antibody Ki-6766
BCL2B-cell CLL/lymphoma 2540
CCND1Cyclin D153
ESR1Estrogen receptor 1480
TCEAL1Transcription elongation factor A (SII)-like 1470
CDKN2ACyclin-dependent kinase inhibitor 2A (p16)390
CYP19A1Cytochrome P450, family 19, subfamily A, polypeptide 1390
INSinsulin360
PTGS2Prostaglandin-endoperoxide synthase 2 (COX2)340
PMS2Postmeiotic segregation increased 2 330
PCNAProliferating cell nuclear antigen320