Long Noncoding RNA Expression Signatures of Metastatic Nasopharyngeal Carcinoma and Their Prognostic Value

Figure 3

The number of differentially expressed lncRNAs at the HOX locus. (a) The transcripts at the HOX locus varied between the four randomly paired M and T groups. A total of 70 lncRNAs were found to be differentially expressed in the metastatic tissues, and 51 coding transcripts were differentially expressed. (b) Different numbers of lncRNAs were detected in the four randomly paired M and T groups. A total of 33 lncRNAs at the HOX locus were found to be upregulated in all groups, and 37 lncRNAs were downregulated. (c) HOTAIR was found to be upregulated in the metastatic tumor samples from all of the groups (); the expression levels of HOTAIR in the metastatic tumors were 4- to 6-fold higher than those in the primary tumors.

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