Research Article
Long Noncoding RNA Expression Signatures of Metastatic Nasopharyngeal Carcinoma and Their Prognostic Value
Table 1
Summary of the microarray data for the metastatic and primary NPC tumors.
| Gene type | RNA expression | Fold-change () | Differentially expressed RNAs () | >20 | 10–20 | 2–10 | Total |
| lncRNA | Upregulated | 65 | 191 | 3,522 | 3,778 | 8,088 | Downregulated | 198 | 225 | 3,887 | 4,310 |
| Enhancer lncRNAs regulating a nearby coding gene | Upregulated | 4 | 5 | 94 | 103 | 462 | Downregulated | 17 | 20 | 322 | 359 |
| HOX cluster | Upregulated | 15 | 5 | 51 | 71 | 121 | Downregulated | 1 | 3 | 46 | 50 |
| lncRNAs regulating a nearby coding gene | Upregulated | 4 | 5 | 94 | 103 | 462 | Downregulated | 17 | 20 | 322 | 359 |
| Rinn lincRNAs | Upregulated | 6 | 14 | 328 | 348 | 1,069 | Downregulated | 33 | 28 | 660 | 721 |
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NPC: nasopharyngeal carcinoma; lncRNA: long noncoding RNA; lincRNA: long intergenic noncoding RNA.
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