Clinical Study
Temozolomide and Radiotherapy versus Radiotherapy Alone in High Grade Gliomas: A Very Long Term Comparative Study and Literature Review
Table 2
Groups A + B and group C: patients’ characteristics.
| | Groups A + B | Group C |
| Patients’ number | 64 | 64 | Age | | | Range | 26–78 years | 29–74 years | Median | 59 years | 60 years | Sex | | | Male | 35 pts | 39 pts | Female | 29 pts | 25 pts | Karnofsky Index | | | Range | 60–90 | 60–90 | Medium | 70 | 70 | Surgery | | | Stereotactic biopsy | 12 pts | 11 pts | Subtotal resection | 30 pts | 35 pts | Total resection | 22 pts | 18 pts | Histology | | | Anaplastic astrocytoma | 21 pts | 14 pts | Glioblastoma multiforme | 43 pts | 50 pts | RT total dose | | | Median | 61 Gy | 59 Gy | Range | 45 Gy–66 Gy | 35 Gy–66 Gy | <50 Gy | 3 pts | 3 pts | ≥50 Gy <60 Gy | 7 pts | 6 pts | ≥60 Gy | 54 pts | 55 pts |
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