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BioMed Research International
Volume 2015, Article ID 621690, 10 pages
Research Article

The Impact of Normalization Methods on RNA-Seq Data Analysis

1Department of Mathematical and Statistical Methods, Poznan University of Life Sciences, 60-637 Poznan, Poland
2Institute of Bioorganic Chemistry, Polish Academy of Sciences, 61-704 Poznan, Poland
3Department of Hematology and Bone Marrow Transplantation, Poznan University of Medical Sciences, 60-569 Poznan, Poland

Received 20 March 2015; Revised 17 May 2015; Accepted 18 May 2015

Academic Editor: Ernesto Picardi

Copyright © 2015 J. Zyprych-Walczak et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

In Supplementary Materials we provide additional details concerning data sets used in the presented research. Furthermore, we provide here additional results not included in the main text for comparison of normalization methods, that include other sources of variation such as GC content and batch correction.

  1. Supplementary Material